George Osborne will say a collection of northern cities linked closer together by new transport infrastructure could "take on the world" as he bids to end London's "unhealthy" economic dominance.
The Chancellor will say in a keynote speech in Manchester today:
We need an ambitious plan to make the cities and towns here in this northern belt radically more connected from east to west - to create the equivalent of travelling around a single global city.
As well as fixing the roads, that means considering a new high speed rail link.
Today I want us to start thinking about whether to build a new high-speed rail connection east-west from Manchester to Leeds.
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Rain will clear eastwards through Sunday but it will remain blustery.
Donald Trump has indicated he does not intend to block the release of thousands of secret files about the assassination of John F Kennedy.
Storm Brian will track off into the north sea later tonight. Blustery tomorrow.