Sulley Muntari and Kevin-Prince Boateng have been expelled from Ghana's World Cup squad for disciplinary problems.
The Ghana Football Association said both had been "suspended indefinitely" in a statement.
AC Milan midfielder Muntari has been punished for an alleged "unprovoked physical attack" on a member of management staff.
Boateng was sent home for "vulgar verbal assaults" towards coach Kewsi Appiah during a training session, for which he had shown "no remorse".
The announcement comes just hours before Ghana play Portugal in their crucial final game in Group G.
For more on this story and all the build-up to Ghana's match with Portugal, visit ITV's World Cup site