David Cameron has admitted that his opposition to Jean-Claude Juncker becoming President of the European Commission has made renegotiating the UK's position in Europe more difficult.
"I do not deny that it has made the task harder and the stakes higher," the Prime Minister writes in today's Daily Telegraph.
However he insisted the Government would not be deterred from trying to reform the EU.
"When we encounter setbacks, we don’t throw in the towel: we redouble our resolve. The task of reforming Europe and securing Britain’s place in a reformed Europe was always going to be a long and tough campaign," Mr Cameron argues.
"You don’t turn around a tanker like the EU with ease; this will be tough, and we’ve always known that," he added.