A senior member of Greater Manchester police has warned the drunken behaviour has become so bad, public safety is "at crisis point" and "sooner or later something horrific is going to happen".
I would not be there past midnight now. I do not believe it is safe there. The situation is at crisis point.
We have got the fastest-growing night-time economy outside London with a new bar opening every weekend. There are a quarter of a million people coming into the city centre to enjoy themselves.
But at four in the morning we will have just half a dozen police officers on duty in the city centre, or even as few as four officers, which is beyond belief.
Cops are getting called to nightclubs to break up fights at 6am on a Sunday morning....Sooner or later something horrific is going to happen.
More top news
ITV News spent the day at the Royal Berkshire Hospital in Reading looking at the lengths it is going to prepare for the winter ahead.
Endris Mohammed must serve a minimum of 33 years after killing his two children with a petrol-soaked cloth before trying to kill his wife.
Three people who had been arrested on suspicion of murder have been released without any further action.