Scientists found a molecule that helps tumours in an especially deadly form of breast cancer have grow and spread. The molecule, known as alpha v beta 6, could be used both to identify at-risk patients and develop new treatments, say scientists.
A study found high levels of alpha v beta 6 in 40% of tumours in women with HER2 positive breast cancer, a form of the disease that does not respond to conventional hormone therapy. These patients were twice as likely to die within five years of diagnosis as those with low levels of the molecule.
In experiments on mice with the same type of breast cancer, scientists used an antibody drug to block activity of alpha v beta 6. Combining the antibody with the drug Herceptin, which targets the cancer-driving HER2 protein, completely eradicated the animals' tumours after six weeks of treatment.
More top news
Harvey Proctor spoke out after police investigating allegations of historical child sex abuse searched his home.
More than a 100 doors have cropped up at the base of the woodland - but managers say they are threatening the enchanted forest.
Jonny Evans and Papiss Cissé are facing likely bans from the FA after appearing to spit at each other during a Premier League game