A man has surrendered to police following an hours-long stand-off in suburban Houston, Texas, local news station KHOU 11 reported.
It follows the deaths of four children and two adults who were shot in a "domestic dispute". Another person was injured in the shooting.
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The Transport Secretary had been due to address the Northern Transport Summit in Manchester.
Police have launched a murder inquiry and two men are in custody.
Foreign Secretary Boris Johnson has faced calls to quit over his opposition to Heathrow expansion.