Jean-Claude Juncker denied being a federalist after being elected as European Commission President.
Mr Juncker told ITV News Political Correspondent Carl Dinnen that he did not want a "United States of Europe". He added: "I will negotiate with David Cameron and others, and will make a fair deal with him".
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The Prime Minister will urge leaders of the other 27 EU states to move on as quickly as possible to talks on Britain's future trade.