President Obama is said to be "aware" of reports of a Malaysian Airlines passenger plane being shot down but could not confirm any of the details, a White House spokesperson said.
Mr Obama directed senior US officials to remain in close contact with Ukrainian officials about the downed plane, the spokesperson added.
Thousands of online users have taken to social media to call for the victims of the Malaysian airliner crash to be returned to loved ones.
United States intelligence officials admitted that they do not know who fired the surface-to-air missile that downed flight MH17.
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