Boris Johnson said today he could not go on "endlessly dodging" questions about his future.
But the Mayor of London played down his chances of success, saying it was "highly likely" he would fail to find a suitable constituency in which to run.
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Charlie Gard's parents have been given until noon on Thursday to reach an agreement with doctors on arrangements for his death.
In a series of tweets, the US president says transgender people will not allowed or accepted to serve their country 'in any capacity'.
The chancellor - having won the argument within Cabinet - has told ITV News he is targeting a swift start to talks on the interim deal.