George Osborne has labelled the defection of Douglas Carswell to Ukip as "regrettable and counter-productive".
Speaking in Brighton today, the Chancellor said that the best way to secure a referendum on Britain's membership of the European Union was to have a Conservative government after the next election.
"That's the choice people are going to face, whether it's at the by-election in Clacton or at the general election next year," Mr Osborne said.
More top news
Colo became a mother of three, grandmother of 16, great-grandmother of 12 and great-great-grandmother of three.
The district's director of homeland security has said officials are planning for 800,000 to 900,000 people to attend the ceremony.
The Supreme Court is set to decide on whether disabled travellers are legally entitled to have priority use of wheelchair spaces on buses.