A leader of Somalia's al Qaeda-linked militants Ahmed Abdi Godane was the target of an US air strike in Somalia, an US official said.
It is not clear whether the Al-Shabaab leader was hit in the strike, the official added.
Six militants were killed in the attack on two vehicles that were heading toward the coastal town of Barawe, Al-Shabab's main base.
Since taking charge in 2008, Godane has restyled the group as a global al Qaeda player - a transformation that was highlighted when it killed at least 67 people in an attack on a Kenyan shopping mall last September.
More top news
A bomb blast reportedly struck a refugee camp in Syria near the border with Jordan causing injuries and deaths.
Donald Trump's claim that the US subsidises the rest of the world to a massive extent should not go unchallenged.
Leader Paul Nuttall is confirmed as UKIP's candidate to contest Stoke Central by-election following Labour MP Tristram Hunt's departure.