The participants are debating the future of North Sea oil and whether an independent Scotland's economy would be better off.
Nicola Sturgeon gets the first big clap of the evening, saying: "If Douglas is right and we are overly dependent on oil and we're too poor to be independent, how has this resource-rich country got into that state?
"That's something wrong with how we're being governed. It's not an argument to stay the same, it's an argument for change."
She accuses Westminster of squandering "much of our oil wealth over the last 40 years".
Campaigners have made their case for and against Scottish independence in a 'Town Hall' style debate.
Things were a lot more civlised in tonight's 'town hall' style debate than in the head-to-heads between Alex Salmond and Alistair Darling.
Some of the leading players in the Yes and No campaigns battle it out in the third major debate on Scottish independence.