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Cardiff scientists discover cancer-fighting compound

Credit: Britta Pedersen/DPA/PA Images

Cardiff University says scientists have developed a new anti-cancer stem cell agent capable of targeting aggressive tumour forming cells common to breast, pancreas, colon and prostate cancers.

The new OH14 compound has been licensed by Tiziana Life Sciences, a British-based pharmaceutical company.

It will now undergo further development before undergoing clinical trials. Researchers say studies have shown it to be effective in eliminating a number of different kinds of cancers cells, including cancer stem cells from breast cancer patients.

The breakthrough comes almost exactly a year after the same research team announced that they had discovered a molecule capable of reversing the spread of malignant breast cancer.

Our computer aided drug screening process has now identified two new classes of anti-cancer agents, specifically targeting two distinct and novel mechanisms underpinning cancer.

– Dr Andrea Brancale, Cardiff University’s School of Pharmacy


Gareth Bale's agent hits back at Roy Keane criticism

Gareth Bale's agent has hit back at Roy Keane, after the television pundit criticised the winger's performance in Real Madrid's Champions League defeat to Juventus.

Credit: PA

Match statistics showed that Bale, who was signed by the Spanish giants for £85.3million in 2013, had the fewest touches and made the fewest passes of any visiting player in Tuesday's 2-1 defeat in Turin.

The Welshman's quiet display prompted former Manchester United captain Keane to say Real Madrid "played with 10 men".

But Bale's representative, Jonathan Barnett, dismissed criticism, saying "Why should we take any notice of irrelevant comments from people who don't know what they are talking about and people who failed in management?

"Gareth only listens to relevant comments. He is at the biggest club in the world. He is one of the best players in the world. He is fine."

Keane, who has managed Sunderland and Ipswich and is now assistant to Martin O'Neill in the Republic of Ireland set-up, told ITV: "Gareth Bale gave them absolutely nothing. He took the easy option every time."

Tattooists in Wales call for greater regulation

Tattooists in Wales are calling for tighter laws and greater regulations on tattoo and piercing parlours.

Tattooing requires no formal qualification Credit: PA

It comes after five people developed serious skin infections after using a piercing and tattoo studio in Newport.

Health officials are currently trying to contact more than five hundred other people known to have used the parlour, to offer a precautionary blood test.

At present, tattooing and piercing requires no formal qualification, however owners of studios must contact their local council in order to get a tattoo, piercing and electrolysis licence.

Although the premises will be inspected, and tattooists must follow laws on hygiene and safety, there are calls for more stringent laws and regulations to protect customers.

The Welsh Government has said it is looking into the practice, and is planning to change the laws with details to come in the summer.

Read More: 'Health fears over skin infections linked to tattoo studio'


Polls open across Wales

Votes will be cast in all 40 Welsh constituencies Credit: ITV News

Polling stations across Wales have opened this morning so people can vote in the General Election.

Booths opened at 7am and voters will have until 10 o'clock tonight to choose their local MP.

The votes will be counted overnight in all forty Welsh constituencies.

Final results will be expected tomorrow.

Lane on M4 at Newport blocked due to 'dog on road'

There are tailbacks on the M4 at Newport this evening as rescuers try to get a dog off the motorway.


One lane is blocked and there is queueing traffic due to three cars and a dog in the road on M4 Westbound between J27 B4591 (Highcross) and J28 A48 / A467 Forge Road (Tredegar Park).

Lane one is blocked by the three cars, who are trying to assist with the retrieval of the dog says Traffic Wales.

Police are holding traffic back, whilst the dog is safely retrieved from the carriageway.

– Traffic Wales
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