Police have charged 46-year-old Mark Bridger with the murder of missing five-year-old April Jones.
Mr Bridger has also been charged with child abduction and attempting to pervert the course of justice.
April disappeared from the Bryn-y-Gog estate in Machynlleth on Monday evening.
Mark Bridger will appear before Aberystwyth Magistrates' Court on Monday morning.
Mr Bridger, a local man who police say is known to the Jones family, was first arrested on suspicion of April's abduction on Tuesday afternoon.
Police confirmed he had been arrested on suspicion of her murder on Friday.
His Land Rover Discovery was also seized by police and is undergoing forensic examination.
Search teams resumed efforts on Saturday morning to locate April after searches were called off on Friday night for the first time since her disappearance on Monday.
Emergency services including the Coastguard, RNLI, RAF mountain rescue and 150 members of mountain rescue teams from across the UK have been searching since April vanished.
Our correspondent Carl Edwards reported live from Aberystwyth shortly after the charge was announced.