Forecasters have warned as much as 10cm of snow could fall in parts of Wales on Sunday, as an amber 'be prepared' warning is in place.
The Met Office has issued the warning, which runs from 4am to 6pm on Sunday.
Areas most likely to be affected are:
According to the Met Office, heavy snow is also likely in the Midlands and parts of Northern and Eastern England, and could reach as much as 20cm on higher ground.
There is the potential for delays to road, rail and air travel and a chance that rural communities could become cut off.
Parts of Wales have already seen some snow this weekend.
In North Wales the British Red Cross helped Betsi Cadwaladr University Health Board by transporting medical staff to hospitals, as well as equipment and blood supplies.
A yellow 'be aware' warning for wind is also in place across much of Wales overnight and into Sunday.
Gusts of up to 70mph are expected in the most exposed coastal locations, with the chance of hail and thunder too.
People are being told to expect delays for high-sided vehicles on exposed routes and bridges and being advised that power cuts are possible.
Conditions proved difficult today for Aberdare Town but they battled through to win 4-2.