There have been four deaths on the M4 in just the last eight days following crashes between Swansea and Newport.
A 56-year-old man died on Thursday in a three car crash between junction 30 turn-off for Cardiff Gate and junction 28 Tredegar Park on the eastbound carriageway.
Gwent Police said a red Honda 4x4, a black Perodua and a silver Audi A6 were involved in the crash.
Jeffrey Paul Williams, from Cwmbran, who was driving the red Perodua died at the scene.
The carriageway was closed for several hours causing tailbacks in the area.
It was the second fatal accident in two days on the M4 between Cardiff and Newport.
On Wednesday evening, a man died between junctions 24 Coldra and 23A Magor.
He suffered serious head injuries after the Audi Q5 he was driving left the motorway.
Last week, Sarah-Jayne Thomas and Timothy Peter Grace, both from Swansea, died when their BMW X5 fatally crashed near Pyle on the M4.
The 28-year-old mum of two died at the scene.
Sarah-Jayne's family said there were 'no words' to explain how much she would be missed.
Timothy Grace was airlifted to hospital but later died at the University Hospital of Wales on Wednesday evening.