'Life-changing' diabetes trial

Researchers at Cardiff University say preventing a form of diabetes could become a reality, if trials prove successful. It aims to slow - or stop - the destruction of insulin-making cells using a vaccine-type treatment.

Cardiff University scientists lead Type 1 diabetes trial

People living with Type 1 diabetes in Wales could be given a life-changing vaccine, thanks to a clincial trial which will take place at Cardiff University.

It's a rare form of the condition which is not related to lifestyle and can cause other health complications.

It's becoming increasingly common and those with diabetes have to inject insulin for life.

David Wood reports.


Cardiff diabetes experts 'hope to find cure' for Type 1

Experts say preventing Type 1 diabetes could 'one day become a reality' if clinical trials of a new 'vaccine' prove successful.

We believe that this immune-based therapy can slow or stop the body from damaging its own insulin-making cells in the pancreas. Research to date shows that the treatment is safe, but we are in the early days and need to learn more about how it works in people with newly-diagnosed Type 1 diabetes. If effective, we can develop further treatments for individuals who are at risk of developing this type of diabetes later in life.

Our ultimate hope is to find a cure for Type 1 diabetes.

– Colin Dayan, Professor of Clinical Diabetes and Metabolism

Cardiff experts in pioneering Type 1 diabetes research

Cardiff University researchers are among a team of experts working on a new 'vaccine' aiming to slow or halt the process that destroys the insulin-making cells in Type 1 diabetes.

Researchers say if clinical trials prove successful it will improve quality of life for those with the condition and could bring experts a step closer to a cure.

Type 1 diabetes usually occurs in childhood when a patient's immune system attacks the body's own insulin-making cells.

Unlike Type 2, it is not linked to poor diet or obesity.

Long-term, diabetes can lead to complications including blindness and amputation.

  • More than 160,000 people in Wales - almost 5% of the population - have been diagnosed with diabetes, although the true figure is believed to be higher as the condition can remain undiagnosed
  • An estimated 5-10% of these have Type 1
  • Type 1 is on the increase in the UK - particularly in children