The sister of missing teenager, Nida Ul-Naseer, has made an emotional appeal for her to get in touch.
Nida was last seen at around 8pm on Saturday 28th December when she went to put the bins out at her family home in Linton Street, Newport.
Naila Anwar, Nida's sister, said: "We miss Nida desperately and want her to come home. We want her to know that she is not in trouble at all and we are worried that she could be unwell because of her condition. What is more worrying is that she missed mum's birthday which is extremely unlike her.
"We would appeal for anyone with any information, no matter how small, to get in touch with police on 101."
Gwent Police say that despite "extensive enquiries" including house to house, leaflet drops, CCTV enquiries and daily local searches, she has not been located.
Police in Newport say they're growing increasingly concerned for the welfare of an 18 year old who went missing last Saturday. Nida Ul-Naseer was last seen on Saturday at her home in the city. Officers have today been making house-to-house enquiries.
Gwent Police say Nida's disappearance is out of character and that no motive has been found to explain her going missing.
– Chief Inspector Daniel Taylor, Gwent Police
As far as we understand it she went out to the bins at the premises. That was the last time she was seen. There is no forensic evidence that she has been taken.
To go missing is particularly out of character for Nida, and officers and her family are increasingly concerned for her welfare due to the fact that she hasn't been in contact, especially over the New Year period.
We are also concerned for Nida because she hasn't taken her medication with her and is likely to become anaemic without it.
Nida is described as Asian-Pakistani in appearance, of slim build, 5ft 3ins tall with long dark hair. She was last known to be wearing blue jeans and a black top.
Anyone with information is asked to call Gwent Police on 101 quoting log number 448 28/12/13.
Police are renewing an appeal to locate 18-year-old Nida Ul-Naseer who went missing from her Newport home since Saturday.
The teenager disappeared after taking the rubbish out at her home in Linton Street that evening. Nida didn't have her medication with her when she vanished.
Searches involving up to 40 officers have been taking place over the past few days in adverse conditions and house-to-house enquiries are continuing today.
Police are growing increasingly concerned about the welfare and whereabouts of 18-year-old Nida Ul-Naseer from Newport, who was reported missing from her address on Linton Street on Saturday.
Nida was last seen at the address at approximately 8pm on 28 December.
She is of Asian-Pakistani appearance and has long dark hair, is slim and five feet three inches tall. She was last known to be wearing blue jeans and a black top.
Police are esepcially concerned for the 18-year-old because she hasn't taken her medication with her and is likely to become anaemic without it.
Police in Newport are appealing for information regarding the whereabouts of 18 year-old Nida Ul-Naseer who has been missing from her Linton Street address since Saturday December 28th.
She was last seen at the address at approximately 8pm and was wearing blue jeans and a black top. Nida is of Asian -Pakistani appearance and has long dark hair, is slim and is five feet three inches tall.
Police are concerned for her welfare as she hasn't taken her medication with her and is likely to become anaemic without it.
If anybody knows of her whereabouts they are asked to call 101 and quote log number 448 28/12/13