The owners of Anglesey Aluminium have confirmed that they are to finally shut their plant outside Holyhead in the next two months.
It is the final twist in a long and slow decline for what had been one of the main employers on the island.
Our Business Correspondent Carole Green reports from the site.
People on Anglesey have reacted to the news of 60 further jobs being lost at Anglesey Aluminium Metals, with fears over the influence on the island's economy more widely.
One man described the loss of employees' spending power as "really sad news" and a woman said "we need people staying in the area" to work.
In 2009, 400 staff were made redundant at Anglesey Aluminium, when it closed its smelting operation.
A re-melt business has operated since then, producing around 250,000 tonnes of metal.
The Anglesey Aluminium Metal (AAM) Board says it has made "extensive efforts" to find options to stay in business, but warned employees last week there was a "strong likelihood" it would have to close.
It says a redundancy programme will include helping employees to find new work, and it will work to try to create a legacy for the local community.
A small team will be kept on to continue de-commissioning, and maintain the site until it is sold.
Anglesey Aluminium Metal has confirmed it will close within the next two months, resulting in 60 jobs being lost.
It says there are "substantial losses" facing the business, from increased competition, material cost increases and a drop in demand for its products.
Anglesey Aluminium Metal says it has advised employees that there is a "strong likelihood" its operation in Holyhead will close.
In 2009, the company closed its smelting operation and 400 members of staff were made redundant. Since then around 100 employees have continued to work on the site.
The company says the consultation process will continue and as soon as it has come to a final decision then employees and various stakeholders will be informed.