Cardiff University says scientists have developed a new anti-cancer stem cell agent capable of targeting aggressive tumour forming cells common to breast, pancreas, colon and prostate cancers.
The new OH14 compound has been licensed by Tiziana Life Sciences, a British-based pharmaceutical company.
It will now undergo further development before undergoing clinical trials. Researchers say studies have shown it to be effective in eliminating a number of different kinds of cancers cells, including cancer stem cells from breast cancer patients.
The breakthrough comes almost exactly a year after the same research team announced that they had discovered a molecule capable of reversing the spread of malignant breast cancer.
Our computer aided drug screening process has now identified two new classes of anti-cancer agents, specifically targeting two distinct and novel mechanisms underpinning cancer.
Cardiff University says experts are helping the immediate rescue efforts in Nepal by providing a real-time assessment of the risk of more landslides after Saturday’s earthquake.
Dr Robert Parker and his team from the University’s School of Earth and Ocean Sciences have developed a computer program calleds ShakeSlide.
The University says organisations like The World Bank and MapAction are now collaborating with Dr Parker directly, working alongside the disaster assessment teams.
The model predictions provide a rapid, first-order assessment of earthquake-triggered landslide hazards, and are currently being used to guide efforts to map landslide damage caused by Saturday’s earthquake in Nepal.
Tests on graphene by a Cardiff University researcher could open up global exploitation of the lightweight ‘wonder’ material.
Graphene is a form of carbon and forms an atomic-scale lattice. It is extremely strong and conducts heat and electricity efficiently. It is used in products from computer chips to super-light aircraft.
But its development has been held back commercially by the cost and difficulty of large-scale production.
Now research by Dr David Morgan, of Cardiff Catalysis Institute, has developed methods of testing and analysing changes in the material.
Dr Morgan has worked alongside South Wales company Perpetuus to test the characteristics of graphene on an industrial scale – a ‘world-first’ for the University.
To the best of our knowledge, this is the first analysis of its kind from raw material to final use of the processed material. The development of graphene and related materials is an exciting and ever-expanding field.
Gold is traditionally regarded as chemically uninteresting because it doesn't react readily with other substances.
But researchers at Cardiff University's School of Chemistry say when broken down into nanoparticles, containing a few hundred atoms, it becomes incredibly reactive.
That makes it an efficient catalyst to speed up chemical and biological processes.
The scientists say they have discovered gold is the best catalyst for making the main ingredient for PVC and it could replace environmentally harmful mercury.
It's hoped using gold in catalysis could mean the better use of raw materials and the ability to generate fuels, plastics and other chemicals from renewables.
Griff Rhys Jones has withdrawn from becoming Cardiff University's new Chancellor just two weeks after an embarrassing debacle which saw his appointment halted at the last minute.
The comedian's appointment was blocked when it emerged current chancellor Sir Martin Evans was not offered the chance to be reappointed.
In a letter to the Vice Chancellor, Professor Colin Riordan, Jones said: "Following the recent decision of the Court of Cardiff University to refer the appointment of a new Chancellor back to the Council, I can see that it is going to need a period of reconsideration and re-evaluation.
"It may well be that the Council wants to re-offer the post to the incumbent, Sir Martin Evans. Sir Martin may decide to take it or step aside.
"I feel, however, that my presence only makes this a more complicated process for everyone concerned. I believe it better that I should withdraw.
"I can't say that I am offering my resignation. I haven't yet been appointed. But I do not want to be further considered for this post. I was honoured to be chosen."
A spokesperson for Cardiff University said: "Cardiff University is very sorry for creating the circumstances that led Griff Rhys Jones to step aside. These events were based solely on internal rules and procedures: our ongoing friendship with Griff Rhys Jones was never in question.
"We are immensely proud of Griff’s continuing work as an Honorary Fellow and Patron to our Sustainable Places Research Institute, and he remains a trusted supporter of the University.
"Council will meet to consider the nomination of a future Chancellor at a meeting on 19 May. Professor Sir Martin Evans has indicated to the Chair of Council his willingness to be considered for nomination for a further term.”
Scientists from Cardiff University are leading new global research into Alzheimer's disease, in a study involving more than one million people around the world.
The £6m project will look into the relationship between genetics and lifestyle in the development of Alzheimer's, hoping to produce the most comprehensive understanding of the disease's risk to date.
"For too long scientists studying Alzheimer's have been working in silos, engaged in a single-minded 'race' to try and beat the disease. That's simply not going to happen unless we pull together," said Principal Investigator Prof Julie Williams from Cardiff University.
"The insights gleaned will pave the way for a new era of therapies. We predict that in future, based on this unrivalled data, GPs may be able run a simple test to analyse a patient's risk of developing Alzheimer's."
"A combination of gene therapy, drugs and lifestyle changes could then be prescribed to reduce that risk."
The research will look at the genetic data of more than a million people over the age of 65, from Europe, America, Australia and Asia.
The first free online course run by Cardiff University has gone live today. Cardiff is the only Welsh university among more than 20 in the UK to sign up to the idea - which is aimed at widening access to higher education.
The first course is about Muslims here - and also aims to spread understanding of their lives, and place in society.
Changes in the sun's energy may have led to natural climate change, according to researchers at Cardiff University.Read the full story ›
Wales' biggest medical school has launched a new education programme designed to train and retain the best doctors in the country. It comes amid fears that too many medics are being lured to other parts of the UK and even abroad with hospitals and GP surgeries here are struggling.
Cardiff has unveiled a new approach to training and retaining doctors in Wales.
Marking the biggest transformation of Cardiff University's medical education programme since its School of Medicine was founded in 1921 the new curriculum aims to cultivate world-class doctors by introducing more community centred learning.
Studies show that medical students who train in underserved areas are more likely to return there to work after graduation.
Professor John Bligh, Dean of Cardiff University's School of Medicine said:
"Ultimately our goal is to modernise teaching with a view to producing world-class clinicians who want to live and work in Wales for the benefit of Welsh patients, and we hope the community-centred learning experience that this curriculum offers will encourage this."
Under the new curriculum, students will be introduced to community-based learning in their first year to ensure early patient contact. Cardiff University School of Medicine is responsible for the graduation of 300 student doctors annually.