Over seventy jobs have been created at a site in Rhymney, with a further seventy jobs safeguarded.
Sharp Clinical Services (UK) Ltd, which provides global clinical trail services, is relocating from its current facilities in Crickhowell.
The company is now expanding, creating 73 jobs and investing £9.5m in a new European Clinical Headquarters in the Rhymney Valley that will double staff numbers.
The investment is backed by £500,000 business finance from the Welsh Government.
Campaigners, who bought a former pub in Crickhowell amid fears a supermarket could be built on the site, find out today if their plans for it will be passed.
The Corn Exchange in Chrickhowell High Street was taken over in November last year and plans were submitted for shops with flats above.
A report for Brecon Beacons National Park Authority will be considered today.
Campaigners say a deal's been reached with the owners of a former pub in Crickhowell High Street amid fears a supermarket could be built on the site.
The Corn Exchange will now be sold to nearly 180 local people. They say the sale's been approved by the board of Punch Taverns Ltd – and the campaigners now have eight weeks to exchange contracts.
After that, they will have six months to gain planning approval for their preferred use of flats above small shops.
Shopkeepers in Crickhowell will be 'boarding-up' their windows on Saturday afternoon, as they continue their protest against plans for a High Street supermarket.
They plan to cover their windows with cardboard and brown paper, and write slogans like "closed" and "out of business due to supermarket".
Those involved say they want to give people an idea of what their High Street could look like if plans to build a 7am to 11pm convenience store go ahead.
Today's action comes after protests on the high street earlier this year, where more than a hundre people turned out to voice their opinions.
The planning application will be decided by the Brecon Beacons National Park.
Officers from Natural Resources Wales have identified the cause of an oil spill, which let 3,500 litres of oil into a river near Crickhowell on Thursday.
The cause of the spill has been traced to a disused oil tank.
The incident has already had a significant impact on the stream, killing many fish and affecting people's gardens.
An investigation is taking place after an oil spill which has polluted approximately 850 metres of river in Crickhowell.
An estimated 3,500 litres of oil has escaped into the river, and the surrounding area, also affecting nearby gardens.
Officers at Natural Resources Wales say they're making efforts to prevent more oil reaching the river, but the impacts are already evident.
Many people called to report the incident earlier today, which is causing an oily sheen on top of the water and a strong odour.
The source of the pollution has been identified, but the oil has now worked its way downstream, affecting the main River Usk.
In tonight's episode:
Carl joins History Chef Ceri Lane at Tretower Court and Castle near Crickhowell.
They'll be making 'hardtack' biscuits, a snack historically eaten by sailors, when they were at sea for months on end.
Carl will also be finding out about the site's rich history, from its time as a grand country house, through to its use as a farm, and eventually its restoration.
Also in tonight's episode:
Andrew Price will be at mountain biking centre Bike Park Wales in Merthyr Tydfil.
Ruth will be exploring the Pembrokeshire Coast, and Hannah is on Saint Catherine's Island in Tenby.
Phillip Stocker's daughter, Charlotte from Abertillery, is stranded in New York after attending her friend's wedding.
Members of a wedding party from Wales who are stranded in New York due to Hurricane Sandy have told ITV Wales their airline has informed them they won't be able to return to the UK until at least Saturday.
Around 30 guests had flown out to America to celebrate the couple's big day but many have since been unable to fly home as flights out of New York have been cancelled.
Some have also had difficulties booking hotels and nine guests have been forced to share one room.