Wales stars Toby Faletau and Hallam Amos were among the try scorers as the Dragons ran in five touchdowns to beat Bordeaux Begles by 40 points to 24 at Rodney Parade this evening in the Amlin Challenge Cup.
Newport Gwent Dragons lost 14-18 to Munster at Rodney Parade. The home side led at half time, thanks to two penalties from Jason Tovey. They extended their lead early in the second half, courtesy of a try by Matthew Pewtner,
Ian Keatley was the standout performer for the visitors, kicking all 18 points for the Irish region.
Ospreys flanker Justic Tipuric scored a try in each half to help his Ospreys side to a 40-17 win over the Dragons. The visitors got off to a good start, with Tom Prydie scoring in the corner after only four minutes.
It did not take the home side long to respond, though, as Dan Biggar made the most of a penalty to put three points on the board for the Ospreys.
There was concern for Wales No. 8 Toby Faletau, who was stretchered off with a head and neck injury.
The Dragons face Italian side in the PRO12 at Rodney Parade tonight.
The Newport side have made a promising start to the season under new director of rugby Lyn Jones, with victories against Ulster and the Scarlets, but defeat to Munster and Edinburgh.
Zebre claimed their first win since being formed, with a thrilling 30-25 victory over Cardiff Blues a fortnight ago.
The Italian side were founded in 2012, and lost every match in their debut PRO12 season.
Lions No8 Toby Faletau is back in the Dragons' line-up, one of several changes in the forwards.
Second row Rob Sidoli, who makes his first start of the season, said: Zebre have "improved a lot. I think that they are a genuine threat as they had a really good result against the Blues which was away for them."
"They have some really good individuals and their core basics are very strong; they will have a good driving line outs and scrum so those are the things we need to get up to speed on quite quick.”
Newport Gwent Dragons have extended the contract of Wales and British and Irish Lions Number 8 Toby Faletau for two years, in a deal that will see him stay with the region until 2016.
"Throughout discussions with Toby I have been extremely impressed with his drive and motivation not only on a personal level but in his commitment to developing the Dragons into the best team in Wales" said Lyn Jones, Dragons Director of Rugby.