Despite trailing Zebre 10-3 at half-time, the Dragons have bounced back with a 14-13 win.
Jevon Groves scored the only try, with penalties by Steffan Jones sealing the victory.
The Dragons are currently drawing with the London Wasps in their Amlin Challenge Cup match at Rodney Parade. The score at half-time is 13-13.
The Ospreys have won their match against the Newport Gwent Dragons at Rodney Parade.
Final score: Dragons 3 - 14 Ospreys
Second row Lloyd Peers has signed a two year deal with the Ospreys.
The 21-year-old made his regional debut away to Exeter in last season's cup. He's captained both the Ospreys and Wales at age-grade level as well as the Ravens in the Principality Premiership.
Injuries in the pack in recent weeks have seen Peers becoming a regular feature in the match day squad for the Ospreys and he has featured in each of the last eight games for the region, including his first taste of Heineken Cup action in the back-to-back games against Toulouse.
He has also been named in the starting XV to play against Newport Gwent Dragons at Rodney Parade today.
Peers said:"I'm really excited about signing this contract. The Ospreys are my home region and I've come through the age grade system here so this is the next big step for me.
" In my position, where there are quality international players ahead of me, I'm definitely learning from the best, people who have been there and done it for the Ospreys and for Wales. It's a great place for me to learn my trade in the second row. "
In the concluding Welsh festive derby the Ospreys are heading down the M4 to Newport to face the Dragons. The Swansea side will be looking to build on their Boxing Day win over the Scarlets. The Dragon will be looking to bounce back from their 12-10 defeat at the Blues 3 days ago.
Kick off 16:15
Dragons back row Dan Lydiate will be leaving the region at the end of the season to take up a contract with an undisclosed European team. Danny has played for the senior side at Rodney Parade since 2006, overcoming a serious neck injury in 2007 which threatened his career.
The Dragons failed to impress against Treviso in the RaboDirect Pro12 this afternoon. A try by Tom Prydie wasn't enough to help the Welsh side to a win. Final score: 32 to 13.
The Dragons outscored Northampton by three tries to two, but lost 30-20 in the LV= Cup this afternoon.
Winger Tonderai Chavhanga got a hat-trick for the home side at Rodney Parade, as the Welsh region led 10-6 at half-time and 15-9 shortly afterwards. Five penalties, a drop goal and a conversion from the Saints' Ryan Lamb put the visitors clear.
Dragons and Wales flanker Dan Lydiate will have surgery today, after breaking his left ankle while playing for the region on Friday night. The 24-year-old had to be helped from the pitch at Rodney Parade just three minutes into the game against Edinburgh.
He is certain to miss his country's autumn internationals. Wales play Argentina, Samoa, New Zealand and Australia on successive weekends in November and early December.
Wales teammates George North and Jamie Roberts have been among those using Twitter to send messages of support to Dan Lydiate, who looks set to miss his country's autumn internationals after breaking his ankle while playing for the Dragons.
Roberts also sent his best wishes to Blues teammate Jason Tovey, who went off injured during his first start for the region last night.