Liberal Democrat education spokesperson Aled Roberts has said important questions about alleged visa fraud involving Glyndwr University have not been answered.
Plaid Cymru education spokesperson Simon Thomas said he is concerned that the Education Minister "could not tell me today whether any other Welsh university could be affected by similar visa failures and the lack of clarity on quality assurance", after Glyndwr University was implicated.
The Education Minister has said has asked the Higher Education Funding Council for Wales to look into Glyndwr University's involvement in alleged student visa fraud - and "wider issues that may be raised by this case."
The North Wales institution has had its right to recruit overseas students suspended, after an investigation into cheating on English language tests, implicating a number of universities and colleges around the UK.
Huw Lewis told Assembly Members the news "has potentially serious implications - not just for the institution - but for the reputation of the Welsh higher education sector as a whole".
He said he has already asked HEFCW to look into it, and will be meeting the body's chair and chief executive on 1 July "to take stock."
The University and College Union has again called for the resignation of the leadership at Glyndwr University, after the North Wales institution was suspended from recruiting overseas students.
Members of the academics union recently voted in favour of strike action, in a dispute over 60 potential job losses.
Union bosses have repeatedly called on the university's vice chancellor and chair of governors to resign because of what they describe as its "increasingly worrying financial situation."
Margaret Phelan from UCU Wales said today: "This latest announcement from the Home Office adds yet more weight to our members' calls for the university leadership to resign. It is clear that there are serious problems with how Glyndwr is being run and those in charge need to be held accountable."
Glyndwr University says it is "deeply upset" to have had its licence to sponsor overseas students has been suspended.
A spokesperson for the North Wales university said: "To be put in this position by external partners is frustrating as Glyndwr University takes its responsibility as a Highly Trusted Sponsor very seriously."
Glyndwr University has had its right to sponsor foreign students suspended, after an investigation into fraud in the student visa system at a large number of universities and colleges around the UK.
Immigration Minister James Brokenshire said an inquiry had found evidence of 'organised criminality' over falsified English language tests, and up to 48,000 overseas students potentially may have falsely obtained English language certificates.
He said 230 students sponsored by North Wales' Glyndwr University have so far been identified as having 'invalid' test results - with another 120 being described as 'questionable.'
Mr Brokenshire said: "the Home Office suspended the highly-trusted sponsor status – that is the right to sponsor foreign students – of Glyndwr University."
"In addition, we have suspended the licences of 57 private further education colleges."
"We have told a further two universities – the University of Bedfordshire and the University of West London – that they are no longer allowed to sponsor new students pending further investigations which will decide whether they too should be suspended."
Over 30 international students who were kicked off their Glyndwr University courses for not doing enough work today failed in a High Court challenge to the college's decision. The mostly Asian accountancy students were part of a wider group who were accused of poor attendance.
But when the case reached the court today, a senior judge rejected their legal challenge to Glyndwr's decision. Each were ordered to pay £500 in legal costs.
The decision means their status in the UK will be reviewed by the Home Office, which will decide whether or not they can stay. However, there was a reprieve for another 23 students, who were told their cases would be looked at again by course bosses.
The students' barrister, Al Mustakim said many of the students had been ill or had been unable to sign in when classes were spot-checked because they were on the toilet.
A team at Glyndwr University St. Asaph are working on a €5m project aiming to help mankind see to within a millisecond of the 'Big Bang'.
A team of 15 engineers are working on prototype mirrors for the 39m telescope, which will be the largest optical and near-infrared telescope in the world.
The telescope, due to be built in Chile in 2023, will eventually need over 900 specialist mirrors.
Glyndwr University says it is determined to secure the manufacturing of the mirrors in north-east Wales. It's claimed the move could create over 60 jobs and contribute €150m to the local economy.