Part of the Heads of the Valleys Road is still closed in both directions after a serious accident involving a motorcyclist.
It happened shortly before 8pm last night between Brynmawr and Ebbw Vale.
The route is likely to be closed for the rush hour for an investigation.
An accident between two lorries has closed the Heads of the Valleys road between Hirwaun and Cefn-Coed-Y-Cymmer.
Emergency services are tackling a fuel spill and traffic is slown in the area.
One is lane closed after an accident involving two vehicles on the A465 Westbound between the Aberdulais Roundabout and the Neath Interchange.
Police are appealing for help following the death of a street lighting worker on the Heads of the Valleys road.
The 42-year-old was installing street lighting on the A465 between Cefn Coed and Baverstocks roundabout when an incident occurred yesterday afternoon. A 39-year-old man has been arrested and bailed pending further enquiries.
The electrician was taken to Prince Charles Hospital in Merthyr at 3pm and later died. South Wales Police and the Health and Safety Executive are both investigating.
South Wales Police would like to hear from anyone travelling through the area between 2pm and 3pm and witnessed work being carried out on the lighting installation prior to the arrival of the emergency services. Please call 101 with information.
A woman's died after a collision involving a van on the Heads of the Valleys Road.
The 41 year-old was walking away from a broken down vehicle with a man at around 7:15pm between Pant and Dowlais.
Her family are being supported by specially trained officers.
South Wales Police are appealing for witnesses, especially a motorist who stopped to speak to the van driver at the scene, to contact South Wales Police Roads Policing Unit via 101.
It is one of South Wales' busiest routes but is also known for its accident blackspots.
A project to upgrade the Heads of the Valleys Road (A465) was given the green light on 1999.
Today the latest stage of the £800million dualling scheme will be officially opened
The Welsh Government says section three of the A465 dualling scheme, Brynmawr to Tredegar, costing £158million, will improve safety and journey times, as well as boost the economy of the region.
It says the 7.8km section of road, joint funded by itself and the EU, has been upgraded from a three lane road to a dual carriageway to alleviate the current issues of poor visibility, congestion, lack of overtaking opportunities and accident hotspots.
Tributes have been paid to a pregnant woman who died in a crash on the Heads of the Valley road on Friday night.
20-year-old Sophie Williams and her unborn baby were killed in a two-car collision between Brynmawr and Ebbw Vale.
20-year-old Sophie Williams and her unborn baby died last night, as she travelled home from a Valentines meal with her fiance, 28-year-old Ben Morgan.
She was due to give birth in just two weeks time.
Ben has returned to the scene of the accident to lay flowers for Sophie and his unborn baby girl.
He's due to be interviewed by police about the tragedy.
Her family in Tredegar, Gwent, were too upset to talk of the tragedy yesterday.
A mum-to-be who was killed in a car crash on the Heads of the Valleys Road yesterday, has been named locally as 20-year-old Sophie Williams from Tredegar.
She was due to have her baby in just two weeks time.
Miss Williams died along with her unborn baby girl as she and her fiance Ben Morgan drove home from a Valentine's meal.
The couple were planning to get married after the baby was born.
They'd been told they were expecting a little girl, and had chosen the name Kayleigh.
The crash happened at 11pm on Friday night during a severe storm at an accident blackspot where roadworks were going on, ironically to turn the road into a dual carriageway, after a high number of fatalities.
Firemen and paramedics freed Sophie from the wreckage and she was taken to Neville Hall Hospital in Abergavenny, but police said doctors were unable to save her and her unborn baby.
Ben and Sophie were in their silver Peugeot 307 when it was in a collision with a blue Peugeot 207 coming the other way.The driver of the other car, a man from Basingstoke, Hampshire, was uninjured but treated for shock.Gwent Police are appealing for anyone who saw the accident to come forward.
Ben is due to be interviewed by police about the tragedy.