Drugs to treat the central nervous system - including painkillers - cost the NHS in Wales more than any other type of drug last year.
Parents of Welsh youngsters with cerebral palsy say their children are being denied a potentially live-changing operation.
As the NHS enters its 66th year, we've been looking at the pressures the service is under and hearing from those who rely on it.
Action Against Medical Accidents says there has been 'welcome improvement' in compliance, but it is 'deeply disappointed by the lack of priority accorded to this vital element of patient safety.'
Whilst there has been a significant and welcome improvement in compliance with patient safety alerts across the boards since we started publishing reports on this issue, it is very concerning that Hywel Dda and Betsi Cadwaladr health boards still have so many alerts outstanding, some of which are years past the deadline for completion and that not a single health board is fully compliant.
– Action Against Medical Accidents
According to Standards for Health Services in Wales there should be 100% compliance. Patients are being left at unnecessary risk. It is possible that some patients may have suffered harm or even died needlessly as a result of alerts not being complied with.
The charity says there is 'urgent need' to review and reform the way patient safety is regulated in Wales.
Action Against Medical Accidents found that there were 61 instances of an alert not being complied with this year, compared to 140 in 2012.
The report also found:
- There were 15 patients safety alerts not complied with over five years past the deadline
- Powys Teaching Health Board had the best rate of compliance, with two alerts outstanding compared with 15 in 2012
- Hywel Dda Health Board had the worst rate with 23 alerts outstanding and Betsi Cadwaladr had 15.
The charity also criticises Health Inspectorate Wales, the body that is responsible for monitoring and regulating the NHS in Wales with regards to safety, saying that no record could be found of them having taken up the issue of non-compliance with any health board.
Patients in Wales are being put at unnecessary risk, according to charity Action Against Medical Accidents. It says health boards aren't taking enough action to deal with safety alerts.
None of Wales' health boards have hit all of their deadlines to comply with so-called patient safety alerts - which are issued when things have gone wrong on the NHS, such as mistakes with high-risk medicines or giving the wrong type of blood.
The charity says that while there has been "significant improved in compliance generally" more needs to be done.
Care for acutely ill patients should be brought to them in future, rather than the patient being moved around the hospital - according to a new report from the Future Hospital Commission.
It is one of 50 recommendations in the report aimed at improving care for acute medical patients.
The independent Future Hospital Commission was established by the Royal College of Physicians in March 2012 to find solutions to the challenges facing the NHS.
Other recommendations include a restructuring of the wards where acutely ill patients are treated, and a new organisational and management structure, whose responsibilities for acutely ill medical patients will stretch out from the hospital into the wider community.
Dr Alan Rees, RCP vice president for Wales, said: "This report has major implications for the clinical practice of physicians, the training of future generations of physicians, for research and - most importantly of all - for patients.
"Its implementation will be a challenge for us all - but implement it we must. Our present and future patients will expect - indeed demand - no less."
Parents of Welsh children with cerebral palsy say that their children are missing out on an operation that could transform their lives.
Wales This Week follows seven-year-old Chase Vaughan as she fights for the operation that could potentially change her life.
There are calls for a special operation to help cerebral palsy sufferers to be made available on the NHS in Wales.
The procedure, known as SDR, helps patients to walk more easily.
At the moment, SDR is only accessible in parts of England, leaving those wanting the surgery here facing a big bill.
Richard Morgan reports
Parents of children with Cerebral Palsy in Wales say that their youngsters are missing out on potentially life-changing surgery. The pioneering operation called Selective Dorsal Rhizotomy, or SDR, is available on the NHS in England but is not funded here in Wales.
Chase Vaughan, is a happy and playful seven year old girl but the nerves in her legs are over active, because she has Cerebral Palsy. It causes severe tightness in her muscles, known as spasticity, so she wears leg braces and after just a few minutes playing she becomes exhausted and frustrated.
As she gets older her condition is deteriorating.
Her mum, Helen says:
“She’s finding it tough. She’s starting to get pain in her legs which she didn’t have before. My concern is obviously it’s just going to get progressively worse and she could end up in a wheelchair."
Helen is convinced that the SDR operation would improve Chase's life and in order to pay for the operation and intensive physiotherapy afterwards, Chase’s family have been trying to raise forty thousand pounds.
Tonight, Wales This Week talks to Helen, and her daughter about their battle to offer Chase the operation which could change her life.
A seven year old girl from Monmouth is learning to walk again after having an operation to relieve the symptoms of cerebral palsy.
Chase Vaughan underwent the procedure known as SDR at Frenchay Hospital in Bristol.
Her family had to raise £40,000 to pay for it, as it's not available on the NHS in Wales.
Richard Morgan reports.
On Monday, we'll be looking at why the SDR treatment isn't available in Wales.
You see more on Chase's story on Wales This Week tomorrow night at 8pm on ITV.
Health services in Wales have hit the headlines with a string of allegations about the quality of care - but what about the quantity of care available? Parents of Welsh children with Cerebral Palsy say that their children are missing out on an operation that could transform their lives.
Wales This Week follows seven year old, Chase Vaughan, as she fights for the operation that could potentially change her life.