It's a return to European competition for the Welsh regions today, with all four sides facing crucial matches. A home win is essential for the Ospreys, who host table-topping Racing Metro in Pool 5.
The Scarlets, second in Pool 3 after 2 games, will hope to get something from their trip to Ulster later this evening.
In the Challenge Cup, it's a clash of two unbeaten teams in Pool 1, where the Blues entertain London Irish at the Arms Park.
Champions Cup: Ospreys v Racing Metro (1500) Ulster v Scarlets (1930)
Challenge Cup: Blues v London Irish (1515)
Wales coach Warren Gatland has put up his most experienced team to take on the Springboks in Durban tomorrow. Mike Phillips and Dan Biggar have been selected to represent Wales at half back. Meanwhile, Jamie Roberts and Jonathan Davies will play midfield.
It's also a big game for Adam Jones who will make his 100th international appearance. The 34-12 win against the Eastern Province Kings on Tuesday puts Wales one up against South Africa. But Gatland says will his team have to play to their full potential if they're to secure a win.
The Wales rugby squad are preparing to leave for South Africa ahead of their two test series later this month. The party fly out today minus injured stars such as captain Sam Warburton, Leigh Halfpenny and Richard Hibbard.
Warren Gatland has selected a 32 man squad for the tour, which gets underway with a warm-up match against Eastern Province Kings in Port Elizabeth next Tuesday. That match is followed by the first test in Durban on June 14, with a further encounter against the Springboks in Nelspruit a week later.
Four uncapped players have been names in the party: fly half or full back Matthew Morgan, utility back Steve Shingler, wing Jordan Williams and scrum half Gareth Davies.
The squad who will prepare for the two-test tour of Japan will be announced by Robin McBryde today. The 'Brave Blossoms' will take on the world's sixth-ranked team in Osaka on June 8 and in Tokyo on June 15.
The Ospreys have announced that Mike Cuddy has stepped down from his role as joint Managing Director with the club. Cuddy, who has been in his role with the rugby region since it was formed, will hand over the day to day running of the club to Roger Blyth and Andrew Hore
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