Campaigners from Saundersfoot who are against plans to build a recycling plant next to a care home have handed over a petition to the Senedd.
Pembrokeshire County Council says the site near New Hedges in Saundersfoot has been identified as the most suitable location for the facility, but protesters say it will ruin the living conditions of 40 residents in the home.
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The peer will attack Prime Minister Theresa May for failing to represent the 48% who voted in favour of Remain.
Paul Flynn, MP for Newport West, will open the debate in Westminster Hall.
It will represent another boost to the region, after the announcement Deca Sealand was chosen for a repair hub for defence aircraft.