Melanie Jane Smith is due to appear before magistrates in Prestatyn on Tuesday morning in connection with a house fire in Prestatyn.
The 42-year-old was charged with four counts of murder, one count of arson with intent to endanger life and threats to commit criminal damage yesterday.
Lee-Anna Shiers died in the fire along with her niece and nephew Bailey and Skye Allen. 15-month-old Charlie Timbrell died from burns suffered in the fire at Liverpool's Alder Hay Hospital.
More top news
A man from Newport who was involved in two separate attempts to smuggle people into the UK has been jailed for five years.
An investigation has been launched after a fire damaged a Deeside hotel.
A fine, dry and sunny start to the week. But be careful, gentle winds mean we'll see extensive fog patches in places.