Cardiff University researchers are among a team of experts working on a new 'vaccine' aiming to slow or halt the process that destroys the insulin-making cells in Type 1 diabetes.
Researchers say if clinical trials prove successful it will improve quality of life for those with the condition and could bring experts a step closer to a cure.
Type 1 diabetes usually occurs in childhood when a patient's immune system attacks the body's own insulin-making cells.
Unlike Type 2, it is not linked to poor diet or obesity.
Long-term, diabetes can lead to complications including blindness and amputation.
- More than 160,000 people in Wales - almost 5% of the population - have been diagnosed with diabetes, although the true figure is believed to be higher as the condition can remain undiagnosed
- An estimated 5-10% of these have Type 1
- Type 1 is on the increase in the UK - particularly in children