Cardiff University researchers are among a team of experts working on a new 'vaccine' aiming to slow or halt the process that destroys the insulin-making cells in Type 1 diabetes.
Researchers say if clinical trials prove successful it will improve quality of life for those with the condition and could bring experts a step closer to a cure.
Type 1 diabetes usually occurs in childhood when a patient's immune system attacks the body's own insulin-making cells.
Unlike Type 2, it is not linked to poor diet or obesity.
Long-term, diabetes can lead to complications including blindness and amputation.
- More than 160,000 people in Wales - almost 5% of the population - have been diagnosed with diabetes, although the true figure is believed to be higher as the condition can remain undiagnosed
- An estimated 5-10% of these have Type 1
- Type 1 is on the increase in the UK - particularly in children
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The owners of what some people claim to be the 'Welsh Holy Grail' are offering a cash reward for the ancient artefact's safe return.
Staying mostly dry overnight with generally light winds, but cloud and wind will gradually increase from the northwest from the early hours.
In the last programme we've been to meet two Welsh entrepreneurs who chose a different route and we visit the Energy Centre at Coleg Menai.