Dr William Roberts, chair of the aBer health campaign group, told ITV News he "welcomes" today's change of Health Minister.
"I look forward to constructive change from a new minister" he says.
The group was set up to oppose proposed changes to services at Bronglais Hospital, Aberystwyth.
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A record crowd of more than 66,000 is expected at the Principality Stadium today for the back-to-back Welsh derbies.
The Welsh Assembly election is less than a week away and the treatment and care of cancer is one of the more contested issues.
Tributes have been paid to an ambulance driver killed in a crash with another ambulance in North Wales.