There has been a serious multi-vehicle collision on the A465 in Neath Port Talbot.
There are reports that a lorry has gone through the central reservation.
The crash happened between the B4242 (Cwmgwrach Roundabout) and B4434 Commercial Road (Resolven Roundabout).
The A465 is closed in both directions.
More top news
Channel 4 claims to have uncovered footage of a Welsh call centre hired by the Tories to directly contact marginal voters.
The average annual car insurance premium in Wales now stands at £539.
The decision was confirmed during an 80-minute coaches' selection meeting on Wednesday.