In conversation with our Political Editor Adrian Masters, the Prime Minister defends his attack on the Welsh Government, saying it is "making mistakes" on the NHS, education and enterprise.
David Cameron says he leads a "very active, very pro-Wales, very pro-enterprise Government", committed to nuclear power on Anglesey and upgrading the M4.
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A record crowd of more than 66,000 is expected at the Principality Stadium today for the back-to-back Welsh derbies.
The Welsh Assembly election is less than a week away and the treatment and care of cancer is one of the more contested issues.
Tributes have been paid to an ambulance driver killed in a crash with another ambulance in North Wales.