Aneurin Bevan Health Board says it has been receiving "walking wounded" casualties at the Royal Gwent Hospital's accident and emergency department in Newport after this morning's M4 crash.
A spokesperson for the health board confirmed ten casualties have been treated for minor injuries in Newport and one has been admitted with more serious injuries.
Two off-site triage centres were also set up in the area following the crash - one at St Julian's clinic and the other at Newport Centre.
More top news
Missed Thursday's Wales at Six? You can catch up here.
A wet and windy night for much of Wales, remaining dry in the far north.
Welsh Premier League side Bangor City have been refused a license to continue playing in Welsh football's top tier.