Leigh Halfpenny, who dislocated his right shoulder against England on Sunday, will undergo surgery tomorrow.
He is expected to be out for up to four months, the WRU says.
Rhys Webb has now been released from the National Squad following his ankle injury, and will be assessed by a medical team at the Ospreys.
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A fine start to the Bank Holiday weekend, but Saturday is shaping up to be the better day with showers moving in on Sunday!
Swansea hope to have injured trio Martin Olsson, Leroy Fer and Jack Cork available for Sunday's Premier League trip to Manchester United.
Samata Ullah used a James Bond style cufflink to hide his support for Islamic State.