The number of people signing up to join the bone marrow donor register in Wales has increased by more than 2500 per cent, compared to this time last year.
The charity behind the register says it's thanks to a family from Cardiff for raising its profile.
The Clark family are looking for a match for eight-year-old Hollie, and to get the message out there they have been asking celebrities to put pants on their heads.
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The former Tory leader is helping to raise awareness of breast cancer in men, by talking about the death of his Llanelli businessman father.
Wales' late brace in the dying moments of the game wasn't enough to come away with a victory against Ireland in Dublin.
The family of Scott Bessant have appealed to the police watchdog regarding the investigation into the incident six months ago.