A panel of judges has ruled that Bristol man Shrien Dewani, who is accused of organising the murder of his wife on their honeymoon, must be extradited to South Africa within 28 days.
The High Court rejected a series of arguments by Mr Dewani's lawyers. He's said to be suffering from post-traumatic stress. From London, here's Bob Constantine.
High court judges have ruled that Dewani must be extradited within 28 days. He is accused of arranging his wife's murder in South Africa but his extradition has been delayed because of his mental health problems.
The Home Office told ITV West Country tonight that he had now exhausted his rights to appeal against extradition. They say the timing of his removal from Britain will be up to the South African authorities and the police.
Honeymoon murder suspect Shrien Dewani has lost his latest legal battle to block extradition to South Africa.
Dewani, 33, from Bristol, has argued that he should not be forced from the UK to face trial over wife Anni's death until he has recovered from mental health problems, including post traumatic stress disorder.
A panel of judges, headed by Lord Chief Justice Lord Thomas, ruled in January that it would not be "unjust and oppressive" to extradite him if an undertaking was given by the South African government relating to how long he would be kept in the country without trial if his illness continues.
The South African authorities have now given the necessary assurances, but Dewani's lawyers returned to London's High Court today to challenge the undertaking.
They also asked for permission to take the case of the millionaire businessman, who is compulsorily detained in hospital under the Mental Health Act, to the Supreme Court, the UK's highest court.
But the judges rejected complaints made about the adequacy of the undertaking and also refused to give the go-ahead for the case to go to the Supreme Court.
Dewani denies any involvement in the killing of 28-year-old Anni, who was shot on the outskirts of Cape Town in November 2010.
Honeymoon murder suspect Shrien Dewani has lost his latest his legal battle to block extradition to South Africa
Dewani is accused of ordering the killing of his 28-year-old wife Anni, who was shot as the couple travelled in a taxi on the outskirts of Cape Town in November 2010.
The Bristol businessman Shrien Dewani is facing extradition to South Africa.
The High Court threw out his appeal to avoid going back to the country, where he's due to stand trial charged with organising the murder of his wife while on their honeymoon.
Lawyers for Mr Dewani argued he should not be sent there because of his mental state.
But judges ruled as long as the South African government pledges to return him to the UK - if he should prove unfit to be tried - he can be extradited.
Caron Bell reports:
Three men have already been convicted over Anni Dewani's death.
South African Xolile Mngeni was convicted of premeditated murder for shooting her. Prosecutors claimed he was a hitman hired by Shrien Dewani to kill his wife, which Dewani has consistently denied.
Taxi driver Zola Tongo was jailed for 18 years after he admitted his part in the killing and another accomplice, Mziwamadoda Qwabe, also pleaded guilty to murder and was handed a 25-year prison sentence.
A lawyer for the South African government said it was "delighted" with the High Court's ruling that has paved the way for honeymoon murder suspect Shrien Dewani to be extradited.
As part of their ruling, the judges, led by Lord Chief Justice Lord Thomas, said an undertaking must be given by the government relating to how long Dewani would be kept in the country without trial.
The lawyer indicated the government would be able to give the undertaking, but needed 14 days "for final clarification".
Murder suspect Shrien Dewani has lost his High Court bid to block his extradition to South Africa until fit to stand trial.
Honeymoon murder suspect Shrien Dewani finds out the result today of his latest legal bid to block his extradition to South Africa until he is fit to stand trial.
Dewani, from Bristol, is accused of ordering the killing of his new wife Anni who was shot on the outskirts of Cape Town in 2010.
So far three men have been convicted over Mrs Dewani's death.
Dewani is fighting a decision for him to be removed from the UK and face proceedings in South Africa until he has recovered from mental health problems including depression and post-traumatic stress.
A decision will be announced later.
Watch mobile phone footage of last night's disturbances in the Easton area of Bristol here:
200 people had gathered in Chelsea Road to celebrate the death of Baroness Thatcher.
Bottles and cans were thrown at officers, six of whom suffered injuries. One remains in hospital.
A police vehicle was damaged and one person was arrested for violent disorder.