Watch our new series featuring ordinary people across the region, whose lives have been altered completely by a life-changing experience.
Our first piece is the story of how a family tragedy 30 years ago started one man's crusade to eradicate the deadly disease of meningitis.
The country's two leading meningitis charities have announced plans to merge. Bristol-based Meningitis UK and the Meningitis Trust in Stroud will join forces next month. They're planning to keep their individual names until a re-launch at the end of the year.
Onor Crummay fell ill with meninigitis B when she was a student at the University of Bristol. It left her with learning difficulties which she managed to battle and now supports Meningitis UK's campaign to get the Government to have children immunised against strain B of bug.
Here is her message about how important a vaccine is.
Hannah Smart's five-year-old daughter Kelsey died of meningitis B last February. She says Kelsey's life would have been saved if she had been immunised.
She was at the launch of a campaign by South Gloucestershire-based charity Meningitis UK to persuade the Government to immunise children against strain B of the bug.