The A4 is closed in both directions due to a jackknifed lorry and fuel spillage between the B4003 (West Kennett) and High Street (Marlborough).
The fuel tank on the lorry has ruptured and there is a large diesel spill on the road near to the Clatford junction.
The road is likely to remain closed for a considerable time.
More top news
It's warming up! Highs of around 23 or 24 degrees this afternoon.
Sergei Skripal and police officer Nick Bailey will reportedly be compensated after their houses were contaminated in the March 4 nerve agent
A teenage boy is also in hospital. Police believe both had suffered adverse reactions to an unknown substance.