A man from Gloucestershire who has the terminal illness Motor Neurone Disease is offering to test new drugs which might help find a cure - or at least a more effective treatment.
Les Halpin says he's prepared to act as a human guinea pig if it'll help medical research.
More top news
A competition is underway to create an official fanfare for Bristol to mark the city's 800th anniversary next year.
Becky Watts's family talk exclusively to ITV about their loss.
Becky Watts' uncle speaks exclusively to ITV News following the arrest of two people on suspicion of her alleged kidnap and murder.