The Dean Academy in the Forest of Dean, Gloucestershire, has identified a number of false widow spiders in the school's computer block, as well as other areas.
A letter to parents on the school's website confirmed that the school would be closed tomorrow.
Vice principal Craig Burns said the academy had taken immediate pest control advice on discovery of the spiders. The letter posted online today read:
We have identified an issue with false widow spiders in the academy in our ICT block and therefore took immediate advice from pest control.
We therefore made the decision to close the ICT block for the whole of today so that pest control could fumigate the area.
Unfortunately, during this afternoon there have been further false widow spiders identified in other areas of the academy.
More top news
Gavin Henson booted an 18-point haul as Bath moved up to second in the Premiership with a 33-23 win over struggling London Irish.
The UK's first "number two" bus is to hit the road powered entirely by human and food waste.
The number of people seeking help with mental health issues after they leave the armed forces is rising here in the West Country.