Yeovil Town Ladies and Bristol City Women will get their Super League campaigns underway this weekend.
The league will be played over winter for the first time this season.
Last season was a memorable one for West Country teams.
Yeovil were crowned champions and Bristol City were runners up, meaning both teams were promoted.
This season they will be competing in WSL 1 - the equivalent of the men's Premier League.
The teams have already experienced playing in the higher league because this year there was a Spring Series which didn't have promotion or relegation.
It was introduced as the women's game moved from a summer season to a winter one.
The Spring Series proved a reality check for both sides because Yeovil failed to win a game, and Bristol City won only once.
Both teams are determined there will not be a repeat performance when they open the new campaign.
Yeovil and Bristol City will be competing against some of the top clubs in Europe such as Manchester City, Arsenal, and Chelsea.
Those clubs operate on much bigger budgets than the two West Country teams.
Yeovil's manager says his side will do all it can to be competitive in WSL1.
Yeovil start their season with a match on Sunday at home to Manchester City whilst Bristol City are away to Chelsea.