Highways England says the M5 northbound between junctions 16 and 14 has been fully reopened following the serious incident in South Gloucestershire on Saturday.
One lane had remained closed between junction 15 and junction 14 while police investigations continued.
The carriageway reopened fully at 5pm.
Highways England says drivers should be aware of residual delays in the area.
Police say they are still investigating the scene of the M5 collision in South Gloucestershire in which four people sadly died.
One lane of the northbound carriageway between J15 and J14 remains closed.
Avon and Somerset Constabulary say this closure is likely to remain in place for a few more hours.
Police say their thoughts remain with the families of all the victims.
A full investigation is being carried out into the circumstances of this collision, which involved a Mercedes box van and two cars.
Three people – a 42-year-old woman and two children, a 12-year-old boy and a 10-year-old girl, remain in a critical but stable condition in hospital.
Family liaison officers are working to support and locate the next of kin of all the victims. It may be some time before formal identification can be concluded. The driver of the lorry, a man in his forties from Worcestershire, has been spoken to and has provided us with an initial statement.
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Bristol city centre will be closed to traffic overnight for three weeks as roads are resurfaced.
The work is part of the city's MetroBus project.
Closures begin on Sunday 10th September and are planned to last three weeks.
The city centre will be closed to traffic from 8pm to 6am, Sundays to Thursdays.
During the night-time closures the following roads will be closed to traffic:
- Colston Avenue
- St Augustine’s Parade
- Broad Quay
- Rupert Street (south of St John’s Bridge)
- Baldwin Street (west of Marsh Street)
- Denmark Street (south of Gaunt’s Lane)
- College Green (south of St George’s Road)
- Anchor Road (east of Lower Lamb Street)
- Cannon’s Road
- St Stephen’s Street
- St Augustine’s Place
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Fire crews are urging people to think more carefully about where they park.Read the full story ›
Two lorries travelling North collided this morning, spilling fuel and closing two lanes of the motorway.Read the full story ›
Companies in Bristol have been displaying their latest driverless cars to the public.Read the full story ›
The friends of a man who died when he was thrown from the cab of his tractor have started a campaign to get farmers to wear seat belts.Read the full story ›
Avon and Somerset Police have released a picture of a woman who appears to be driving her car with a with a parrot on her shoulder.
Talk about back seat driving!
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