The Pilgrims twice led against Port Vale in their third round replay but eventually lost 3-2.
John Sheridan has agreed 'in principle' to stay on as Plymouth Argyle manager. Here's a look at his tenure so far.
Property developer and Plymouth Argyle chairman James Brent has announced multi-million pound redevelopment plans for Home Park.
Tonight's League Two match between Newport County and Plymouth Argyle has been postponed because of a waterlogged pitch.
A pitch inspection will be held at 12:30 this afternoon to see if Plymouth Argyle's match against Newport can go ahead.
Plymouth Argyle have been knocked out of the FA Cup. They were beaten by Port Vale in tonight's third round replay at Home Park.
Andres Gurrieri put the Pilgrims ahead in the second minute. Vale equalised on the half hour, and although Argyle regained the lead six minutes later through captain Conor Hourihane, the League One side scored twice in the second half to win 3-2. Reuben Reid also missed a late penalty.
Vale will now face Championship side Brighton in the fourth round.
Plymouth Argyle go in search tomorrow of a much needed Christmas cheer at Home Park. John Sheridan's Pligrims host Bury but last won a home league game one month ago.
He insist they've been playing well without scoring goals and that this busy period is a real opportunity to move up the table.
The brother of the Formula One racing driver, Lewis Hamilton, has been showing that good driving runs in the family - he's just beaten Plymouth Albion and Argyle players in a go-karting challenge. Nicolas Hamilton is also a professional racing driver.
He has Cerebral Palsy and couldn't walk unaided until a few years ago. But he isn't letting that hold him back.
Plymouth Argyle manager John Sheridan says he's pleased with the way the team has been performing and will "stick to the game plan" ahead of their match against Hartlepool:
A 21st minute goal by Conor Hourihane gave Plymouth Argyle the lead in the "dockyard derby" against Portsmouth in the early kick off at Home Park. Pompey's Yassin Moutaouakil inadvertently chested a cross into Hourihane's path and he volleyed home..
Portsmouth equalised when Jed Wallace cooly placed his shot past McCormick in the 39th minute.
The draw for the second round of the Johnstone's Paint Trophy has been made.
The South West's last remaining side in the competition, Plymouth Argyle, will travel to League One side Swindon Town.
Argyle reached the second round after beating Cheltenham on penalties in the week.
The match will be played in the second week of October.
The £50m redevelopment of Plymouth Argyle's Home Park ground has come a step closer today (Wednesday) when Councillors approved a vital land deal.
They agreed to transfer an acre of land next to the ground to the developer.
The Council said it hoped in return, the redevelopment would create 400 new jobs as well as 600 building jobs.
Work on the major project could start this autumn.