The British Red Cross in Bristol is saying goodbye to the international warehouse and its staff after 12 years.
The international emergency response unit warehouse is moving to bigger premises in Northamptonshire.
The move will free up space for locally-based Red Cross services, including a larger suite of first aid training rooms.
The Red Cross’s other health and social care and emergency response services remain unaffected.
The Red Cross is celebrating its 150th anniversary, and a vital part of the operation is based in South Gloucestershire.
The Bristol Emergency Response centre at Warmley has sent out thousands of emergency aid, hygiene and food parcels over the years.
The treacherous driving conditions are causing problems for many. The Red Cross has been using four by four vehicles to get through the snow in Somerset so patients can keep vital hospital appointments.
As our Somerset correspondent David Woodland reports, most Red Cross drivers are volunteers and they've had to borrow four-wheel drives to help those who need it most.