Badger culling can legally get underway from Saturday.
The licenced culls in two parts of the South West are aimed at trying to reduce the levels of TB in cattle.
DEFRA says about 5,000 badgers will be shot during the pilot cull period.
If it is a success, it is expected to be rolled out in other parts of the country.
But protestors say they will be out in force, to try to disrupt the cull.
Seth Conway reports: