One pedestrian has been taken to Derriford Hospital, via air ambulance, with serious injuries. There are thought to be 7 casualties in total including the driver of the vehicle.
Six of the casualties are being taken to the RD&E for treatment. Fore Street is closed at Long Lane and what is described as the top end of Beer.
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A light breeze winds across the region, with clouds and rainy spells. There may be mist or fog in places.
Tonight will see light winds across the region, accompanied by cloudy skies, outbreaks of rain and mist and fog spreading north overnight.
Campaigners fighting the abuse chose Bristol bus station to try to educate the public on a growing problem.