Darron Gibson has withdrawn from the Republic of Ireland squad for the World Cup qualifier against Kazakhstan after telling manager Giovanni Trapattoni he is still suffering the disappointment of Euro 2012.
The 24-year-old midfielder was initially named in the 23-man party which will fly out to the former Soviet republic next week for the game on Friday night.
Sunderland's David Meyler has been called up in his place and will meet up with the rest of the squad in Dublin tomorrow.
Trapattoni said: "When Darron informed me of his decision to withdraw, I called him to talk things through.
"As we embark upon a brand new campaign, he is very much in my plans and I consider him to be a key player for Ireland for this campaign.
"However, Darron has said that although he doesn't want to let anyone down, he doesn't feel ready to ready to return to the squad for this fixture after the disappointment of Euro 2012.
"I hope that Darron will take this time to reflect positively on his international career, and return to us in time for the Germany game in October."
Gibson went to Poland and Ukraine with Ireland, but was restricted to a seat on the bench as they slipped to successive defeats at the hands of Croatia, Spain and Italy.
Trapattoni indicated in the aftermath of the finals that Gibson, along with the likes of James McCarthy and James McClean, would have bigger parts to play in his future plans.
The Italian has seen the vastly-experienced Shay Given and Damien Duff announce their retirements from international football in recent weeks and although Richard Dunne has confirmed his intention to play on once he has recovered from injury, the manager is having to contemplate significant change.
He will hope Gibson does eventually return to the fold with Group C favourites Germany due in Dublin on October 12, four days before his side heads for the Faroe Islands.
The Republic, who only just missed out on the last World Cup finals after a controversial play-off defeat by France, will look to open the latest campaign with a positive result in Kazakhstan before heading for London to face Oman in a friendly at Craven Cottage during the forthcoming international break.