The England international limped out of Saturday's 1-0 Barclays Premier League victory at Southampton with a dead leg, while fellow midfielder Sebastian Larsson has a knee problem, although manager Martin O'Neill is hoping both will make the game.
Skipper Lee Cattermole (knee) remains on the long-term casualty list along with defender Wes Brown (also knee), but David Meyler has been recalled from his loan spell at Hull to bolster O'Neill's midfield resources.
Striker Mario Balotelli (illness) could also come back into contention while left-backs Aleksandar Kolarov and Gael Clichy will hope to overcome niggles.
Forward Samir Nasri is out with a hamstring injury while right-back Micah Richards (knee) and midfielder Jack Rodwell (hamstring) remain on the long-term casualty list.
Sunderland: Mignolet, Westwood, Bardsley, Kilgallon, O'Shea, Cuellar, Bramble, Rose, Gardner, Colback, McClean, Larsson, Johnson, Vaughan, Sessegnon, Meyler, Saha, Campbell, Wickham, McFadden, Fletcher.
Man City: Hart, Pantilimon, Wright, Zabaleta, Maicon, Lescott, Kompany, K Toure, Nastasic, Rekik, Kolarov, Clichy, Milner, Barry, Y Toure, Garcia, Silva, Sinclair, Aguero, Tevez, Balotelli, Dzeko, Razak.