Manchester United manager Sir Alex Ferguson has confirmed he will make changes for Monday's FA Cup fifth round tie with Reading at Old Trafford.
Javier Hernandez, Ashley Young and Nani are amongst the most obvious candidates to come in, with skipper Nemanja Vidic also primed for a recall.
Paul Scholes (knee) definitely misses out.
Reading manager Brian McDermott will fully utilise his squad for Monday night's FA Cup fifth-round tie at Manchester United.
Forwards Adam Le Fondre and Noel Hunt are back in contention after coming off the bench in last week's Barclays Premier League defeat at Stoke.
Striker Jason Roberts (hip) and goalkeeper Alex McCarthy (shoulder) continue their rehabilitation.
Man United: Lindegaard, De Gea, Amos, Rafael, Smalling, Evans, Vidic, Ferdinand, Jones, Buttner, Evra, Cleverley, Giggs, Anderson, Carrick, Kagawa, Young, Nani, Valencia, Hernandez, Rooney, Welbeck, Van Persie.
Reading: Federici, Harte, Mariappa, Pearce, Kelly, McAnuff, McCleary, Leigertwood, Kebe, Blackman, Le Fondre, Akpan, Pogrebnyak, Hunt, Morrison, Taylor, Karacan, Shorey.